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Browse POLICY Project (1995-2006) Materials

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  • The prevention of mother-to-child transmission (PMTCT) model is a computer program that evaluates the costs and benefits of intervention programs to reduce vertical transmission of HIV. As part of the intervention, the PMTCT model contains seven possible treatment choices: long course ZDV; short course ZDV following the Thailand, PETRA Arm A, and PETRA Arm B regimens; intrapartum and neonatal ZDV only; the HIVNET 012 regimen of single dose nevirapine to the mother and child; and universal nevirapine (nevirapine provided to all women and children at the time of delivery without checking for HIV status). In addition to these seven treatment options, the model also allows the percentage of women undergoing a Cesarean section, as well as the percentage of women that breastfeed their infants exclusively and with mixed breastfeeding and food supplements, to be specified. For each of the treatment options, PMTCT requires various data, including the costs of these interventions, and possible user fees to offset these costs. The vertical transmission rate of HIV is provided as a program default and also varies by treatment option, mode of delivery, and method of feeding.