Oral pre-exposure prophylaxis (PrEP) provision is a priority intervention for high HIV prevalence settings and populations at substantial risk of HIV acquisition. This mathematical modelling analysis estimated the impact, cost and cost-effectiveness of scaling up oral PrEP in 13 countries. These modelling results can inform prioritization, target-setting and other decisions related to oral PrEP scale-up within combination prevention programmes. We caution against extensive use given limitations in cost data and implementation approaches. This analysis highlights some of the immediate challenges facing countries—for example, trade-offs between overall impact and cost-effectiveness—and emphasizes the need to improve data availability and risk assessment tools to help countries make informed decisions.
Pretorius, C, M. Schnure, J. Dent, R. Glaubius, G. Mahiane, et al. 2020. “Modelling Impact and Cost-effectiveness of Oral Pre-exposure Prophylaxis in 13 Low-resource Countries.” Journal of the International AIDS Society. https://doi.org/10.1002/jia2
English External LinkMarch 2020
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